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Honokiol induces superoxide production by targeting mitochondrial respiratory chain complex I in Candida albicans

BACKGROUND: Honokiol, a compound extracted from Magnolia officinalis, has antifungal activities by inducing mitochondrial dysfunction and triggering apoptosis in Candida albicans. However, the mechanism of honokiol-induced oxidative stress is poorly understood. The present investigation was designed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Lingmei, Liao, Kai, Wang, Dayong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576747/
https://ncbi.nlm.nih.gov/pubmed/28854218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184003
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