Azole Susceptibility and Transcriptome Profiling in Candida albicans Mitochondrial Electron Transport Chain Complex I Mutants

Mitochondrial dysfunction in pathogenic fungi or model yeast causes altered susceptibilities to antifungal drugs. Here we have characterized the role of mitochondrial complex I (CI) of Candida albicans in antifungal susceptibility. Inhibitors of CI to CV, except for CII, increased the susceptibility...

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Detalhes bibliográficos
Main Authors: Sun, Nuo, Fonzi, William, Chen, Hui, She, Xiaodong, Zhang, Lulu, Zhang, Lixin, Calderone, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535965/
https://ncbi.nlm.nih.gov/pubmed/23147730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01520-12
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