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An Azole-Tolerant Endosomal Trafficking Mutant of Candida albicans Is Susceptible to Azole Treatment in a Mouse Model of Vaginal Candidiasis

We recently reported that a Candida albicans endosomal trafficking mutant continues to grow after treatment with the azole antifungals. Herein, we report that the vps21Δ/Δ mutant does not have a survival advantage over wild-type isolates after fluconazole treatment in a mouse model of vaginal candid...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Peters, Brian M., Luna-Tapia, Arturo, Tournu, Hélène, Rybak, Jeffrey M., Rogers, P. David, Palmer, Glen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444139/
https://ncbi.nlm.nih.gov/pubmed/28348159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00084-17
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