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Endosomal Trafficking Defects Can Induce Calcium-Dependent Azole Tolerance in Candida albicans
The azole antifungals arrest fungal growth through inhibition of ergosterol biosynthesis. We recently reported that a Candida albicans vps21Δ/Δ mutant, deficient in membrane trafficking through the late endosome/prevacuolar compartment (PVC), continues to grow in the presence of the azoles despite t...
Tallennettuna:
| Julkaisussa: | Antimicrob Agents Chemother |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118996/ https://ncbi.nlm.nih.gov/pubmed/27645241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01034-16 |
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