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Genetic Analysis of Azole Resistance in the Darlington Strain of Candida albicans

High-level azole resistance in the Darlington strain of Candida albicans was investigated by gene replacement in C. albicans and expression in Saccharomyces cerevisiae. We sequenced the ERG11 gene, which encodes the sterol C(14)α-demethylase, from our copy of the Darlington strain. Both alleles cont...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kakeya, Hiroshi, Miyazaki, Yoshitsugu, Miyazaki, Haruko, Nyswaner, Katherine, Grimberg, Brian, Bennett, John E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC101590/
https://ncbi.nlm.nih.gov/pubmed/11036010
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