Genetic Analysis of Azole Resistance in the Darlington Strain of Candida albicans

High-level azole resistance in the Darlington strain of Candida albicans was investigated by gene replacement in C. albicans and expression in Saccharomyces cerevisiae. We sequenced the ERG11 gene, which encodes the sterol C(14)α-demethylase, from our copy of the Darlington strain. Both alleles cont...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Kakeya, Hiroshi, Miyazaki, Yoshitsugu, Miyazaki, Haruko, Nyswaner, Katherine, Grimberg, Brian, Bennett, John E.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Mechanisms of Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.2985-2990.2000
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