Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

Mitochondria use oxygen as the final acceptor of the respiratory chain, but its incomplete reduction can also produce reactive oxygen species (ROS), especially superoxide. Acute hypoxia produces a superoxide burst in different cell types, but the triggering mechanism is still unknown. Herein, we sho...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Hernansanz-Agustín, Pablo, Ramos, Elena, Navarro, Elisa, Parada, Esther, Sánchez-López, Nuria, Peláez-Aguado, Laura, Cabrera-García, J. Daniel, Tello, Daniel, Buendia, Izaskun, Marina, Anabel, Egea, Javier, López, Manuela G., Bogdanova, Anna, Martínez-Ruiz, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430576/
https://ncbi.nlm.nih.gov/pubmed/28511347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.025
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