Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

Mitochondria use oxygen as the final acceptor of the respiratory chain, but its incomplete reduction can also produce reactive oxygen species (ROS), especially superoxide. Acute hypoxia produces a superoxide burst in different cell types, but the triggering mechanism is still unknown. Herein, we sho...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Hernansanz-Agustín, Pablo, Ramos, Elena, Navarro, Elisa, Parada, Esther, Sánchez-López, Nuria, Peláez-Aguado, Laura, Cabrera-García, J. Daniel, Tello, Daniel, Buendia, Izaskun, Marina, Anabel, Egea, Javier, López, Manuela G., Bogdanova, Anna, Martínez-Ruiz, Antonio
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430576/
https://ncbi.nlm.nih.gov/pubmed/28511347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.025
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