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Honokiol induces superoxide production by targeting mitochondrial respiratory chain complex I in Candida albicans

BACKGROUND: Honokiol, a compound extracted from Magnolia officinalis, has antifungal activities by inducing mitochondrial dysfunction and triggering apoptosis in Candida albicans. However, the mechanism of honokiol-induced oxidative stress is poorly understood. The present investigation was designed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Sun, Lingmei, Liao, Kai, Wang, Dayong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576747/
https://ncbi.nlm.nih.gov/pubmed/28854218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184003
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