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Human iPSC glial mouse chimeras reveal glial contributions to schizophrenia

In this study, we investigated whether intrinsic glial dysfunction contributes to the pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial chimeric mice using glial progenitor cells (GPCs) produced from induced pluripotent stem cells derived from patients with childhood...

Полное описание

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Библиографические подробности
Опубликовано в: :Cell Stem Cell
Главные авторы: Windrem, Martha S., Osipovitch, Mikhail, Liu, Zhengshan, Bates, Janna, Chandler-Militello, Devin, Zou, Lisa, Munir, Jared, Schanz, Steven, McCoy, Katherine, Miller, Robert H., Wang, Su, Nedergaard, Maiken, Findling, Robert L., Tesar, Paul J., Goldman, Steven A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576346/
https://ncbi.nlm.nih.gov/pubmed/28736215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.06.012
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