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Activity‐Based Probes for HECT E3 Ubiquitin Ligases

Activity‐based probes (ABPs) have been used to dissect the biochemical/structural properties and cellular functions of deubiquitinases. However, their utility in studying cysteine‐based E3 ubiquitin ligases has been limited. In this study, we evaluate the use of ubiquitin‐ABPs (Ub‐VME and Ub‐PA) and...

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Pubblicato in:Chembiochem
Autori principali: Byrne, Robert, Mund, Thomas, Licchesi, Julien D. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575557/
https://ncbi.nlm.nih.gov/pubmed/28425671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700006
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