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Functional dissection of an HECT ubiquitin E3 ligase

Ubiquitination is one of the most prevalent protein posttranslational modifications in eukaryotes, and its malfunction is associated with a variety of human diseases. Despite the significance of this process, the molecular mechanisms that govern the regulation of ubiquitination remain largely unknow...

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Autors principals: Lu, Jin-ying, Lin, Yu-yi, Qian, Jiang, Tao, Sheng-ce, Zhu, Jian, Pickart, Cecile, Zhu, Heng
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861892/
https://ncbi.nlm.nih.gov/pubmed/17951556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700353-MCP200
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