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Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase

Ubiquitin (Ub)-protein ligases (E3s) frequently modify their substrates with multiple Ub molecules in the form of a polyubiquitin (poly-Ub) chain. Although structurally distinct poly-Ub chains (linked through different Ub lysine (Lys) residues) can confer different fates on target proteins, little i...

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Hlavní autoři: Wang, Min, Cheng, Dongmei, Peng, Junmin, Pickart, Cecile M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440828/
https://ncbi.nlm.nih.gov/pubmed/16601690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601061
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