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Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase
Ubiquitin (Ub)-protein ligases (E3s) frequently modify their substrates with multiple Ub molecules in the form of a polyubiquitin (poly-Ub) chain. Although structurally distinct poly-Ub chains (linked through different Ub lysine (Lys) residues) can confer different fates on target proteins, little i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440828/ https://ncbi.nlm.nih.gov/pubmed/16601690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601061 |
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