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Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis
Individual ubiquitin (Ub)–protein ligases (E3s) cooperate with specific Ub-conjugating enzymes (E2s) to modify cognate substrates with polyubiquitin chains. E3s belonging to the Really Interesting New Gene (RING) and Homologous to E6-Associated Protein (E6AP) C-Terminus (HECT) domain families utiliz...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356336/ https://ncbi.nlm.nih.gov/pubmed/16341092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600895 |
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