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Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins

HECT domain E3 ubiquitin ligases of the NEDD4 family control many cellular processes, but their regulation is poorly understood. They contain multiple WW domains that recognize PY elements. Here, we show that the small PY-containing membrane proteins, NDFIP1 and NDFIP2 (NEDD4 family-interacting prot...

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Detalhes bibliográficos
Main Authors: Mund, Thomas, Pelham, Hugh R B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680872/
https://ncbi.nlm.nih.gov/pubmed/19343052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.30
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