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Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins

HECT domain E3 ubiquitin ligases of the NEDD4 family control many cellular processes, but their regulation is poorly understood. They contain multiple WW domains that recognize PY elements. Here, we show that the small PY-containing membrane proteins, NDFIP1 and NDFIP2 (NEDD4 family-interacting prot...

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Main Authors: Mund, Thomas, Pelham, Hugh R B
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680872/
https://ncbi.nlm.nih.gov/pubmed/19343052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.30
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