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Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled
Dishevelled is a pivot in Wnt signal transduction, controlling both β-catenin-dependent transcription to specify proliferative cell fates, and cell polarity and other non-nuclear events in post-mitotic cells. In response to Wnt signals, or when present at high levels, Dishevelled forms signalosomes...
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| Publicado no: | Open Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703060/ https://ncbi.nlm.nih.gov/pubmed/26701932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150185 |
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