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Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration

Microtubule-stabilizing drugs have gained popularity for treating injured adult axons, the rationale being that increased stabilization of microtubules will prevent the axon from retracting and fortify it to grow through inhibitory molecules associated with nerve injury. We have posited that a bette...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Austin, Timothy O., Matamoros, Andrew J., Friedman, Joel M., Friedman, Adam J., Nacharaju, Parimala, Yu, Wenqian, Sharp, David J., Baas, Peter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575010/
https://ncbi.nlm.nih.gov/pubmed/28852085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10250-z
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