Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration

Microtubule-stabilizing drugs have gained popularity for treating injured adult axons, the rationale being that increased stabilization of microtubules will prevent the axon from retracting and fortify it to grow through inhibitory molecules associated with nerve injury. We have posited that a bette...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Austin, Timothy O., Matamoros, Andrew J., Friedman, Joel M., Friedman, Adam J., Nacharaju, Parimala, Yu, Wenqian, Sharp, David J., Baas, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575010/
https://ncbi.nlm.nih.gov/pubmed/28852085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10250-z
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