Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration

Microtubule-stabilizing drugs have gained popularity for treating injured adult axons, the rationale being that increased stabilization of microtubules will prevent the axon from retracting and fortify it to grow through inhibitory molecules associated with nerve injury. We have posited that a bette...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Austin, Timothy O., Matamoros, Andrew J., Friedman, Joel M., Friedman, Adam J., Nacharaju, Parimala, Yu, Wenqian, Sharp, David J., Baas, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575010/
https://ncbi.nlm.nih.gov/pubmed/28852085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10250-z
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