Targeting MYC sensitizes malignant mesothelioma cells to PAK blockage-induced cytotoxicity

Clinical management of malignant mesothelioma (MM) is very challenging due to marked resistance of this tumor to chemotherapy. Various mechanisms lead to a less than ideal drug concentration inside of MM cells, diminishing cytotoxicity. Consequently, single cytotoxic drugs achieve very modest respon...

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Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Tan, Yinfei, Sementino, Eleonora, Chernoff, Jonathan, Testa, Joseph R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574944/
https://ncbi.nlm.nih.gov/pubmed/28861328
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