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Targeting PAK1

p21-activated kinase 1 (PAK1) has attracted much attention as a potential therapeutic target due to its central role in many oncogenic signaling pathways, its frequent dysregulation in cancers and neurological disorders, and its tractability as a target for small-molecule inhibition. To date several...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Semenova, Galina, Chernoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973817/
https://ncbi.nlm.nih.gov/pubmed/28202661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160134
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