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Pak Signaling in the Development and Progression of Cancer

p21-activated kinases (Paks) are positioned at the nexus of several oncogenic signaling pathways. Overexpression or mutational activation of Pak isoforms is frequently seen in various human tumors, and recent data suggests that excessive Pak activity drives many cellular processes that are the hallm...

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Detalhes bibliográficos
Main Authors: Radu, Maria, Semenova, Galina, Kosoff, Rachelle, Chernoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115244/
https://ncbi.nlm.nih.gov/pubmed/24505617
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