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p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts

The p21 (Cdc42/Rac) activated kinase Pak1 regulates cell morphology and polarity in most, if not all, eukaryotic cells. We and others have established that Pak's effects on these parameters are mediated by changes in the organization of cortical actin. Because cell motility requires polarized r...

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Detalhes bibliográficos
Main Authors: Sells, Mary Ann, Boyd, Jonathan T., Chernoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133181/
https://ncbi.nlm.nih.gov/pubmed/10330410
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