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p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts

The p21 (Cdc42/Rac) activated kinase Pak1 regulates cell morphology and polarity in most, if not all, eukaryotic cells. We and others have established that Pak's effects on these parameters are mediated by changes in the organization of cortical actin. Because cell motility requires polarized r...

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Dettagli Bibliografici
Autori principali: Sells, Mary Ann, Boyd, Jonathan T., Chernoff, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133181/
https://ncbi.nlm.nih.gov/pubmed/10330410
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