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DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling
The transcriptional output of the Sonic Hedgehog morphogenic pathway is orchestrated by three Krüppel family transcription factors, Gli1 to -3, which undergo extensive posttranslational modifications, including ubiquitination and SUMOylation. Here, we report that the sentrin-specific peptidase SENP1...
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| 出版年: | Mol Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574045/ https://ncbi.nlm.nih.gov/pubmed/28630282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00579-16 |
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