SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis

Small ubiquitin-like modifier (SUMO) modification of proteins (SUMOylation) and deSUMOylation have emerged as important regulatory mechanisms for protein function. SENP1 (SUMO-specific protease) deconjugates SUMOs from modified proteins. We have created SENP1 knockout (KO) mice based on a Cre–loxP s...

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Detalhes bibliográficos
Main Authors: Yu, Luyang, Ji, Weidong, Zhang, Haifeng, Renda, Matthew J., He, Yun, Lin, Sharon, Cheng, Ee-chun, Chen, Hong, Krause, Diane S., Min, Wang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882842/
https://ncbi.nlm.nih.gov/pubmed/20457756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092215
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