Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue patterns during development. Here, we report endocytic sorting signals for the receptor Patched1 (Ptch1), comprising two ‘PPXY’ motifs, that...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yue, Shen, Tang, Liu-Ya, Tang, Ying, Tang, Yi, Shen, Qiu-Hong, Ding, Jie, Chen, Yan, Zhang, Zengdi, Yu, Ting-Ting, Zhang, Ying E, Cheng, Steven Y
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2014
विषय:
Developmental Biology and Stem Cells
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080449/
https://ncbi.nlm.nih.gov/pubmed/24925320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02555
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