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Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes
Although high-throughput sequencing can elucidate the genetic basis of hereditary cardiomyopathy, direct interventions targeting pathological mutations have not been established. Furthermore, it remains uncertain whether homology-directed repair (HDR) is effective in non-dividing cardiomyocytes. Her...
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| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571012/ https://ncbi.nlm.nih.gov/pubmed/28839205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09716-x |
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