Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes

Although high-throughput sequencing can elucidate the genetic basis of hereditary cardiomyopathy, direct interventions targeting pathological mutations have not been established. Furthermore, it remains uncertain whether homology-directed repair (HDR) is effective in non-dividing cardiomyocytes. Her...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ishizu, Takamaru, Higo, Shuichiro, Masumura, Yuki, Kohama, Yasuaki, Shiba, Mikio, Higo, Tomoaki, Shibamoto, Masato, Nakagawa, Akito, Morimoto, Sachio, Takashima, Seiji, Hikoso, Shungo, Sakata, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571012/
https://ncbi.nlm.nih.gov/pubmed/28839205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09716-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados