Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration accompanied by dilated cardiomyopathy. Recently, abnormality of yes-associated protein (YAP) has been reported as the pathogenesis of muscle degeneration of DMD; however YAP activity remains unclear in dystrophic h...

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Publicado en:Sci Rep
Main Authors: Yasutake, Hideki, Lee, Jong-Kook, Hashimoto, Akihito, Masuyama, Kiyoshi, Li, Jun, Kuramoto, Yuki, Higo, Shuichiro, Hikoso, Shungo, Hidaka, Kyoko, Naito, Atsuhiko T., Miyagawa, Shigeru, Sawa, Yoshiki, Komuro, Issei, Sakata, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121946/
https://ncbi.nlm.nih.gov/pubmed/33990626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89603-8
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