Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration accompanied by dilated cardiomyopathy. Recently, abnormality of yes-associated protein (YAP) has been reported as the pathogenesis of muscle degeneration of DMD; however YAP activity remains unclear in dystrophic h...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yasutake, Hideki, Lee, Jong-Kook, Hashimoto, Akihito, Masuyama, Kiyoshi, Li, Jun, Kuramoto, Yuki, Higo, Shuichiro, Hikoso, Shungo, Hidaka, Kyoko, Naito, Atsuhiko T., Miyagawa, Shigeru, Sawa, Yoshiki, Komuro, Issei, Sakata, Yasushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121946/
https://ncbi.nlm.nih.gov/pubmed/33990626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89603-8
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