An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

The ubiquitination mediated by ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2), and ubiquitin ligase (E3) cascade is crucial to protein degradation, transcription regulation, and cell signaling in eukaryotic cells. The high specificity of ubiquitination is regulated by the intera...

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Foilsithe in:Nat Commun
Main Authors: Li, Yang, Xie, Ping, Lu, Liang, Wang, Jian, Diao, Lihong, Liu, Zhongyang, Guo, Feifei, He, Yangzhige, Liu, Yuan, Huang, Qin, Liang, Han, Li, Dong, He, Fuchu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570908/
https://ncbi.nlm.nih.gov/pubmed/28839186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00299-9
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