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Enzyme–substrate relationships in the ubiquitin system: approaches for identifying substrates of ubiquitin ligases

Protein ubiquitylation is an important post-translational modification, regulating aspects of virtually every biochemical pathway in eukaryotic cells. Hundreds of enzymes participate in the conjugation and deconjugation of ubiquitin, as well as the recognition, signaling functions, and degradation o...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: O’Connor, Hazel F., Huibregtse, Jon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545068/
https://ncbi.nlm.nih.gov/pubmed/28455558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2529-6
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