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Ubiquitin‐Activated Interaction Traps (UBAITs) identify E3 ligase binding partners
We describe a new class of reagents for identifying substrates, adaptors, and regulators of HECT and RING E3s. UBAITs (Ubiquitin‐Activated Interaction Traps) are E3‐ubiquitin fusion proteins and, in an E1‐ and E2‐dependent manner, the C‐terminal ubiquitin moiety forms an amide linkage to proteins th...
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| Publicado no: | EMBO Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693525/ https://ncbi.nlm.nih.gov/pubmed/26508657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540620 |
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