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Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins

Eukaryotic genomes contain numerous non-functional high-affinity sequences for transcription factors. These sequences potentially serve as natural decoys that sequester transcription factors. We have previously shown that the presence of sequences similar to the target sequence could substantially i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kemme, Catherine A., Marquez, Rolando, Luu, Ross H., Iwahara, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569922/
https://ncbi.nlm.nih.gov/pubmed/28486614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx387
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