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Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins

Eukaryotic genomes contain numerous non-functional high-affinity sequences for transcription factors. These sequences potentially serve as natural decoys that sequester transcription factors. We have previously shown that the presence of sequences similar to the target sequence could substantially i...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Kemme, Catherine A., Marquez, Rolando, Luu, Ross H., Iwahara, Junji
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569922/
https://ncbi.nlm.nih.gov/pubmed/28486614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx387
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