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Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts

The dynamic interaction of DNA methylation and transcription factor binding in regulating spatiotemporal gene expression is essential for embryogenesis, but the underlying mechanisms remain understudied. In this study, using mouse models and integration of in vitro and in vivo genetic and epigenetic...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhang, Donghong, Wu, Bingruo, Wang, Ping, Wang, Yidong, Lu, Pengfei, Nechiporuk, Tamilla, Floss, Thomas, Greally, John M., Zheng, Deyou, Zhou, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389556/
https://ncbi.nlm.nih.gov/pubmed/27956497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1258
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