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Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts

The dynamic interaction of DNA methylation and transcription factor binding in regulating spatiotemporal gene expression is essential for embryogenesis, but the underlying mechanisms remain understudied. In this study, using mouse models and integration of in vitro and in vivo genetic and epigenetic...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Zhang, Donghong, Wu, Bingruo, Wang, Ping, Wang, Yidong, Lu, Pengfei, Nechiporuk, Tamilla, Floss, Thomas, Greally, John M., Zheng, Deyou, Zhou, Bin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389556/
https://ncbi.nlm.nih.gov/pubmed/27956497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1258
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