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Hypoxia-induced Suppression of c-Myc by HIF-2α in Human Pulmonary Endothelial Cells Attenuates TFAM Expression
The adaptive response to hypoxia is mediated in large part by stabilization of the hypoxia-inducible factors, HIF-1α and HIF-2α. A hallmark of this response is the metabolic shift to decreased oxidative phosphorylation and increased glycolysis. We hypothesized that hypoxic responses would include a...
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| Vydáno v: | Cell Signal |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568858/ https://ncbi.nlm.nih.gov/pubmed/28709643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.07.008 |
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