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Hypoxia-induced Suppression of c-Myc by HIF-2α in Human Pulmonary Endothelial Cells Attenuates TFAM Expression

The adaptive response to hypoxia is mediated in large part by stabilization of the hypoxia-inducible factors, HIF-1α and HIF-2α. A hallmark of this response is the metabolic shift to decreased oxidative phosphorylation and increased glycolysis. We hypothesized that hypoxic responses would include a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Signal
Päätekijät: Zarrabi, Ali J., Kao, Derrick, Nguyen, Dustin T., Loscalzo, Joseph, Handy, Diane E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568858/
https://ncbi.nlm.nih.gov/pubmed/28709643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.07.008
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