Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer

Bone metastases occur in over 75% of patients with advanced breast cancer and are responsible for high levels of morbidity and mortality. In this study, ex vivo expanded cytotoxic Vγ9Vδ2 T cells isolated from human peripheral blood were tested for their anti-cancer efficacy in combination with zoled...

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Veröffentlicht in:Cancer Lett
Hauptverfasser: Zysk, Aneta, DeNichilo, Mark O., Panagopoulos, Vasilios, Zinonos, Irene, Liapis, Vasilios, Hay, Shelley, Ingman, Wendy, Ponomarev, Vladimir, Atkins, Gerald, Findlay, David, Zannettino, Andrew, Evdokiou, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568037/
https://ncbi.nlm.nih.gov/pubmed/27865798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.11.013
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