Zoledronic Acid Inhibits Both the Osteolytic and Osteoblastic Components of Osteosarcoma Lesions in a Mouse Model

PURPOSE: To evaluate the efficacy of zoledronic acid (ZOL) against osteosarcoma (OS) growth, progression, and metastatic spread using an animal model of human OS that closely resembles the human disease. EXPERIMENTAL DESIGN: Human K-HOS or KRIB OS cells, tagged or untagged with a luciferase reporter...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Labrinidis, Agatha, Hay, Shelley, Liapis, Vasilios, Ponomarev, Vladimir, Findlay, David M., Evdokiou, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568249/
https://ncbi.nlm.nih.gov/pubmed/19401351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1616
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