Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo

Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor (TNF) receptor superfamily that binds to the ligand for receptor activator of nuclear factor κB (RANKL) and inhibits bone resorption. OPG can also bind and inhibit the activity of the TNF‐related apoptosis‐inducing ligand (Apo2L...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Zinonos, Irene, Labrinidis, Agatha, Lee, Michelle, Liapis, Vasilios, Hay, Shelley, Ponomarev, Vladimir, Diamond, Peter, Findlay, David M, Zannettino, Andrew CW, Evdokiou, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568243/
https://ncbi.nlm.nih.gov/pubmed/20818644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.244
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