(*)Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability

When cultured with sufficient nutrient supply, engineered cartilage synthesizes proteoglycans rapidly, producing an osmotic swelling pressure that destabilizes immature collagen and prevents the development of a robust collagen framework, a hallmark of native cartilage. We hypothesized that mechanic...

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Foilsithe in:Tissue Eng Part A
Main Authors: Nims, Robert J., Cigan, Alexander D., Durney, Krista M., Jones, Brian K., O'Neill, John D., Law, Wing-Sum A., Vunjak-Novakovic, Gordana, Hung, Clark T., Ateshian, Gerard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Mary Ann Liebert, Inc. 2017
Ábhair:
Special Focus: Strategic Directions in Musculoskeletal Tissue Engineering
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567877/
https://ncbi.nlm.nih.gov/pubmed/28193145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2016.0467
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