(*)Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability

When cultured with sufficient nutrient supply, engineered cartilage synthesizes proteoglycans rapidly, producing an osmotic swelling pressure that destabilizes immature collagen and prevents the development of a robust collagen framework, a hallmark of native cartilage. We hypothesized that mechanic...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part A
Main Authors: Nims, Robert J., Cigan, Alexander D., Durney, Krista M., Jones, Brian K., O'Neill, John D., Law, Wing-Sum A., Vunjak-Novakovic, Gordana, Hung, Clark T., Ateshian, Gerard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Special Focus: Strategic Directions in Musculoskeletal Tissue Engineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567877/
https://ncbi.nlm.nih.gov/pubmed/28193145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2016.0467
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