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Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β

Transforming growth factor beta (TGF-β) has become one of the most widely utilized mediators of engineered cartilage growth. It is typically exogenously supplemented in the culture medium in its active form, with the expectation that it will readily transport into tissue constructs through passive d...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Albro, Michael B., Nims, Robert J., Durney, Krista M., Cigan, Alexander D., Shim, Jay J., Vunjak-Novakovic, Gordana, Hung, Clark T., Ateshian, Gerard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968414/
https://ncbi.nlm.nih.gov/pubmed/26599624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.10.018
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