Shearing of Synovial Fluid Activates Latent TGF-β

OBJECTIVE: TGF-β is synthesized in an inactive latent complex that is unable to bind to membrane receptors, thus unable to induce a cellular biological response until it has been activated. In addition to activation by chemical mediators, recent studies have demonstrated that mechanical forces may a...

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Detalhes bibliográficos
Main Authors: Albro, Michael B., Cigan, Alexander D., Nims, Robert J., Yeroushalmi, Kevin J., Oungoulian, Sevan R., Hung, Clark T., Ateshian, Gerard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448789/
https://ncbi.nlm.nih.gov/pubmed/22858668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.07.006
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