Synthesis Rates and Binding Kinetics of Matrix Products in Engineered Cartilage Constructs Using Chondrocyte-Seeded Agarose Gels

Large-sized cartilage constructs suffer from inhomogeneous extracellular matrix deposition due to insufficient nutrient availability. Computational models of nutrient consumption and tissue growth can be utilized as an efficient alternative to experimental trials to optimize the culture of large con...

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Bibliographic Details
Main Authors: Nims, Robert J., Cigan, Alexander D., Albro, Michael B., Hung, Clark T., Ateshian, Gerard A.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017010/
https://ncbi.nlm.nih.gov/pubmed/24284199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2013.10.044
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