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Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs

Cartilage tissue engineering is a promising approach to treat osteoarthritis. However, current techniques produce tissues too small for clinical relevance. Increasingly close-packed channels have helped overcome nutrient transport limitations in centimeter-sized chondrocyte-agarose constructs, yet o...

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Bibliografische gegevens
Gepubliceerd in:J Biomech
Hoofdauteurs: Cigan, Alexander D., Nims, Robert J., Vunjak-Novakovic, Gordana, Hung, Clark T., Ateshian, Gerard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922491/
https://ncbi.nlm.nih.gov/pubmed/27255605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2016.05.020
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