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NUTRIENT CHANNELS AND STIRRING ENHANCED THE COMPOSITION AND STIFFNESS OF LARGE CARTILAGE CONSTRUCTS

A significant challenge in cartilage tissue engineering is to successfully culture functional tissues that are sufficiently large to treat osteoarthritic joints. Transport limitations due to nutrient consumption by peripheral cells produce heterogeneous constructs with matrix-deficient centers. Inco...

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Detalhes bibliográficos
Publicado no:J Biomech
Main Authors: Cigan, Alexander D., Nims, Robert J., Albro, Michael B., Vunjak-Novakovic, Gordana, Hung, Clark T., Ateshian, Gerard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261053/
https://ncbi.nlm.nih.gov/pubmed/25458579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2014.10.017
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