Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity

The type 2 transmembrane serine protease matriptase is involved in many pathophysiological processes probably via its enzymatic activity, which depends on the dynamic relationship between zymogen activation and protease inhibition. Matriptase shedding can prolong the life of enzymatically active mat...

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Vydáno v:PLoS One
Hlavní autoři: Tseng, Chun-Che, Jia, Bailing, Barndt, Robert, Gu, Yayun, Chen, Chien-Yu, Tseng, I-Chu, Su, Sheng-Fang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567652/
https://ncbi.nlm.nih.gov/pubmed/28829816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183507
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