Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity

The type 2 transmembrane serine protease matriptase is involved in many pathophysiological processes probably via its enzymatic activity, which depends on the dynamic relationship between zymogen activation and protease inhibition. Matriptase shedding can prolong the life of enzymatically active mat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tseng, Chun-Che, Jia, Bailing, Barndt, Robert, Gu, Yayun, Chen, Chien-Yu, Tseng, I-Chu, Su, Sheng-Fang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567652/
https://ncbi.nlm.nih.gov/pubmed/28829816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183507
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